• Group sales were up by 5%1 at constant exchange rates (CER) (stable in CHF) in the first half, driven by the high demand for both our medicines and diagnostics; excluding COVID-19-related products, sales increased by 8%
  • Group sales growth accelerated to 9% (7% in CHF) in the second quarter as the decline in COVID-19-related sales no longer had an impact on overall sales
  • Pharmaceuticals Division sales rose by 5% in the first half; strong growth of 8% in the base business2 excluding COVID-19 effect was driven by continued high demand for our newer medicines to treat severe diseases; eye medicine Vabysmo was again the major growth driver
  • Diagnostics Division sales rose by 5%, while growth in the base business2, which excludes the impact of COVID-19 sales, was 9% due to higher demand for immunodiagnostic products
  • Core operating profit increased by 11% (4% in CHF), core earnings per share grew by 9% (1% in CHF) and IFRS net income was down by 4%
  • Outlook for 2024 earnings raised
  • Highlights:
    • US approval for Vabysmo prefilled syringe for three leading causes of vision loss and PiaSky for a rare blood condition; US filing acceptance for Susvimo in two leading causes of vision loss in adults with diabetes
    • US FDA Breakthrough Therapy Designation, priority review and filing acceptance for inavolisib (breast cancer); US FDA Breakthrough Therapy Designation for Columvi (blood cancer)
    • EU approval for Ocrevus subcutaneous injection (multiple sclerosis) and Alecensa (early-stage lung cancer); positive EU opinion for Vabysmo (retinal vein occlusion, a severe eye disease) and PiaSky in paroxysmal nocturnal haemoglobinuria (PNH), a rare blood condition; EU marketing authorisation application review initiated for Elevidys (Duchenne muscular dystrophy)
    • Positive phase III data for Columvi (blood cancer), five-year data for Evrysdi (spinal muscular atrophy), four-year data for Vabysmo (DME, a severe eye disease), phase Ib data for CT-388 (obesity) and phase I data for CT-996 (obesity)
    • CE mark for Accu-Chek SmartGuide, an AI-enabled continuous glucose monitoring solution offering critical predictions to people living with diabetes
    • US approval of human papillomavirus (HPV) self-collection solution, the first available in the country to allow women to privately collect their samples; two new WHO prequalifications for cervical cancer screening tools, including HPV self-collection solution
    • Launch of new analytical units, cobas c 703 and cobas ISE neo, to deliver higher testing capacity and increased automation for laboratories
    • US emergency use authorisation for cobas liat four-in-one molecular test for some of the most prevalent respiratory viruses

Roche CEO Thomas Schinecker: “Our strong sales growth in the first half of 2024 reflects the high demand for our innovative medicines and diagnostics. In the second quarter, we saw an acceleration of our growth momentum as Group sales were no longer impacted by the decline in COVID-19 sales, resulting in very strong sales growth for the Group. Based on our strong half-year results, we are raising our earnings outlook for the full year.

We also received a number of important regulatory approvals in the last three months, including EU approval for Alecensa for a form of early-stage lung cancer, as well as for the subcutaneous injection of Ocrevus, which provides an additional treatment option for multiple sclerosis. I am particularly pleased about the US approval for the ready-to-use prefilled syringe of our eye medicine Vabysmo, which continues to be our main growth driver. In diagnostics, our new Accu-Chek SmartGuide solution for continuous blood glucose monitoring uses artificial intelligence to provide reliable blood glucose level forecasts for several hours.”

Key figures CHF millions % change
January–June 2024 2023 At CER1 In CHF
Group sales 29,848 29,779 5 0
Pharmaceuticals Division sales 22,637 22,511 5 1
Diagnostics Division sales 7,211 7,268 5 -1
Core operating profit 11,293 10,911 11 4
Core EPS – diluted (CHF) 10.23 10.10 9 1
IFRS net income 6,697 7,563 -4 -11

Outlook for 2024 earnings raised
Roche expects an increase in Group sales in the mid single digit range (CER).

Core earnings per share are targeted to grow in the high single digit range (CER), excluding the impact from the resolution of tax disputes in 2023.

Roche expects to further increase its dividend in Swiss francs.

Group results
In the first half of 2024, Group sales were up by 5% at CER (stable in CHF) at CHF 29.8 billion. While the appreciation of the Swiss franc slowed against most currencies, it had an adverse impact on the results presented in Swiss francs compared to constant exchange rates.

Core operating profit grew by 11% (4% in CHF), driven by higher sales and cost management.

Core earnings per share increased by 9% (1% in CHF). IFRS net income was 4% lower (-11% in CHF), mainly due to the impairment of product and technology intangible assets in the research or development phase following strategic decisions. In addition, the IFRS result was impacted by the base effect of the release of provisions related to litigations in the first half of 2023.

The Pharmaceuticals Division base business grew by 8%, while divisional sales increased by 5% to CHF 22.6 billion, driven primarily by higher sales of Vabysmo (severe eye diseases), with growing demand for Phesgo (breast cancer), Ocrevus (multiple sclerosis), Polivy (blood cancer) and Evrysdi (spinal muscular atrophy). These five medicines together generated total sales of CHF 7.3 billion, an increase of CHF 1.8 billion (CER) from the first half of 2023.

The eye medicine Vabysmo, launched in early 2022, remained a major growth driver, generating sales of CHF 1.8 billion on growing demand in all regions, mainly the US.

Sales of MabThera/Rituxan, Herceptin and Avastin decreased by a combined CHF 0.4 billion (CER) as the impact of biosimilar competition slowed further. Sales of the COVID-19 medicine Ronapreve were minimal compared with CHF 0.5 billion in the first half of 2023.

In the United States, sales grew by 5% as increased sales of Vabysmo, Polivy, Ocrevus and Xolair (food allergies) were partially offset by the continued decline in sales of medicines for which patent protection has expired. Vabysmo achieved CHF 1.4 billion in sales, showing a high uptake in both new patients and patients switching from other medications.

In Europe, sales surged by 10%, driven by demand for Vabysmo in France, the UK and Germany as well as by the continued uptake of Phesgo, Ocrevus, Hemlibra (haemophilia) and Evrysdi. This was partially offset by lower sales of medicines for which patent protection has expired and of Perjeta (breast cancer) due to ongoing conversion of patients to Phesgo.

Sales in Japan were down 28%, mainly due to the base effect of the supply of Ronapreve (COVID-19) to the government in the first half of 2023. Excluding this effect, sales in Japan were 5% lower as strong demand for Phesgo was more than offset by the impact of government price cuts.

Sales in the International region increased by 17%, led by demand for Perjeta, Evrysdi, Phesgo and Tecentriq (cancer immunotherapy). Sales in China increased by 14%, driven by Perjeta, Alecensa (lung cancer), Avastin (liver cancer), Xofluza (influenza) and Polivy.

The Diagnostics Division base business grew by 9%, while divisional sales increased by 5% to CHF 7.2 billion. Immunodiagnostic products, which include cardiac, oncology and thyroid tests, were the main growth drivers (11%). Additional growth impetus came from clinical chemistry (8%), advanced staining techniques in oncology (11%) and from companion diagnostics (46%).

The continued good growth in the division’s base business was partially offset by the expected sales decline of COVID-19-related products. Sales of COVID-19 tests further declined to CHF 0.1 billion in the first half of 2024 from CHF 0.4 billion in the corresponding period last year.

Sales growth was reported across all regions, with the Europe, Middle East and Africa (EMEA) region growing by 4%, North America by 5%, Asia-Pacific by 3% and Latin America by 16%.

Pharmaceuticals: key developments

Compound Milestone
Regulatory
Susvimo
Severe eye disease 		Roche to reintroduce Susvimo in the US for people with neovascular age-related macular degeneration (nAMD)

  • The FDA has approved updates to Susvimo, which will be available to US retina specialists and patients with nAMD in the coming weeks
  • Susvimo offers the first alternative to regular eye injections that are standard of care for nAMD, which impacts 20 million people worldwide and can cause blindness if left untreated
  • By continuously delivering medicine to the eye through a refillable implant, Susvimo is the first and only approved nAMD treatment shown to maintain vision with two refills a year
More information: Media Release, 8 July 2024
Vabysmo prefilled syringe
Severe eye diseases 		FDA approves Vabysmo prefilled syringe (PFS) for three leading causes of vision loss

  • Vabysmo PFS is the first and only syringe prefilled with an FDA-approved bispecific antibody to treat retinal conditions that can cause blindness
  • Designed to simplify administration, Vabysmo PFS provides retina specialists a ready-to-use option
  • Vabysmo PFS will be available for people living with nAMD, DME and RVO
More information: Media Release, 5 July 2024
Vabysmo
Severe eye diseases 		Vabysmo gets CHMP recommendation for third indication retinal vein occlusion (RVO)

  • Positive recommendation is based on two phase III studies. In addition to robust retinal drying with Vabysmo, these data show early and sustained vision improvements, which are non-inferior to aflibercept
  • If approved, Vabysmo would be the first and only bispecific antibody treatment available for the nearly one million people with RVO in the European Union
  • Vabysmo is already approved in the US and Japan for RVO and in more than 95 countries around the world for people living with nAMD and DME
More information: Media Release, 28 June 2024
PiaSky
Rare blood condition 		CHMP recommends EU approval of PiaSky for people with PNH, a rare, life-threatening blood condition

  • If approved, PiaSky would be the first monthly subcutaneous (SC) treatment for paroxysmal nocturnal haemoglobinuria (PNH) in the EU
  • Additionally, with the option of self-administration, PiaSky may provide an alternative to existing intravenous (IV) C5 inhibitors, potentially helping to reduce treatment burden
  • The recommendation is based on the results of the COMMODORE 2 study, where SC PiaSky given every month demonstrated equivalent disease control and comparable safety to IV eculizumab given every two weeks
More information: Media Release, 28 June 2024
Ocrevus
Multiple sclerosis 		Ocrevus subcutaneous administration approved by European Commission as first and only twice-a-year injection for relapsing and primary progressive multiple sclerosis

  • Ocrevus subcutaneous (SC) injection offers a new, 10-minute administration of Ocrevus with comparable efficacy and safety to intravenous infusion (IV)
  • Ocrevus SC provides an additional treatment option without the need for IV facilities, expanding accessibility for patients
  • Roche is working closely with national health systems in Europe to ensure people with multiple sclerosis can access Ocrevus SC as quickly as possible
More information: Media Release, 25 June 2024
Elevidys
Duchenne muscular dystrophy 		EMA has initiated review of the Elevidys Marketing Authorisation application for the treatment of Duchenne muscular dystrophy (DMD)

  • If approved, Elevidys is expected to be the first and only gene therapy available in Europe to address the underlying cause of Duchenne muscular dystrophy
  • Elevidys is already approved in the US, Qatar, Kuwait, UAE, Oman and Bahrain
More information: Investor Update, 24 June 2024
Alecensa
Lung cancer

 		European Commission approves Alecensa as the first and only targeted adjuvant treatment for people with ALK-positive early-stage lung cancer

  • Alecensa reduced the risk of disease recurrence or death by an unprecedented 76% in people with ALK-positive resected non-small cell lung cancer (NSCLC), as demonstrated in the phase III ALINA study
  • The approval of Alecensa addresses an urgent unmet need in the early-stage setting where about half of all people experience disease recurrence following surgery, despite adjuvant chemotherapy
  • Early diagnosis and treatment of lung cancer can reduce the burden associated with progressive disease and give people the best possible chance of cure
More information: Media Release, 10 June 2024
Inavolisib
Breast cancer 		FDA grants priority review to inavolisib for advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation

  • Priority review recognises the best-in-class potential of the inavolisib-based regimen for patients in urgent need of new treatment options
  • Additional analyses of INAVO120 were presented in an oral abstract session at the 2024 American Society of Clinical Oncology Annual Meeting
  • The target action date for the FDA decision is 27 November 2024
More information: Media Release, 29 May 2024
Inavolisib
Breast cancer 		FDA grants Breakthrough Therapy Designation to inavolisib for advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation

  • The designation is based on phase III INAVO120 results, showing the inavolisib-based regimen more than doubled progression-free survival compared with palbociclib and fulvestrant alone in the first-line setting
  • Approximately 40% of people with hormone receptor-positive breast cancer have a PIK3CA mutation and often face poorer prognosis and resistance to endocrine treatment
  • This is the 29th Breakthrough Therapy Designation for Roche’s oncology portfolio, a testament to our enduring ambition to deliver transformative medicines for patients
More information: Media Release, 21 May 2024


Phase III, pivotal and other key readouts; data presentations
Susvimo
Severe eye disease 		New data for Susvimo demonstrate sustained efficacy in two serious diabetic eye conditions

  • Two-year phase III data presented at the 2024 American Society of Retina Specialists (ASRS) annual meeting show the potential of Susvimo as an alternative to eye injections to treat diabetic macular oedema (DME) and diabetic retinopathy (DR)
  • Safety data were consistent with the known safety profile for Susvimo in people with DME and DR
  • Additionally, the FDA has accepted the filing application for Susvimo in DME and DR based on one-year Pagoda and Pavilion study data
  • Susvimo is a unique therapeutic approach that provides continuous delivery of medicine to the eye through a refillable implant
More information: Media Release, 18 July 2024
Vabysmo
Severe eye diseases 		Vabysmo shows extended durability, continued efficacy and a consistent safety profile in long-term diabetic macular oedema (DME) study

  • More than 90% of patients had absence of DME after four years in a pre-specified exploratory endpoint
  • People treated with Vabysmo sustained vision gains and anatomical improvements, with almost 80% receiving treatment at intervals of three or four months, in an exploratory analysis
  • The study met all primary endpoints, showing safety data were consistent with the known safety profile of Vabysmo
  • This is the largest long-term extension dataset in DME to date, demonstrating consistent positive results in a highly prevalent eye condition
More information: Media Release, 17 July 2024
CT-996
Obesity 		Roche announces positive phase I results for its oral GLP-1 receptor agonist CT-996 for the treatment of people with obesity

  • After four weeks of treatment, CT-996 demonstrated clinically meaningful weight loss of -7.3% (weight loss in placebo -1.2%; p < 0.001)
  • Pharmacokinetic data support a once-daily oral dosing regimen for CT-996
  • The safety and tolerability profile was consistent with that of other oral GLP-1 receptor agonists and no unexpected safety signals were observed
More information: Media Release, 17 July 2024
Tiragolumab
Lung cancer 		Update on phase II/III SKYSCRAPER-06 study in metastatic non-squamous non-small cell lung cancer

  • SKYSCRAPER-06, evaluating tiragolumab plus Tecentriq and chemotherapy, did not meet the primary endpoints of progression-free survival at primary analysis and overall survival at first interim analysis
  • The combination of tiragolumab plus Tecentriq and chemotherapy showed reduced efficacy compared to the comparator arm
  • Safety was consistent with previous studies; however, Roche intends to halt the trial due to reduced efficacy compared to the comparator arm
More information: Media Release, 4 July 2024
Columvi
Blood cancer 		Phase III STARGLO study demonstrates Columvi significantly extends survival in people with relapsed or refractory diffuse large B-cell lymphoma

  • The study met its primary endpoint of overall survival with a 41% reduction in the risk of death in people with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) treated with Columvi plus chemotherapy
  • This Columvi combination could provide a much-needed off-the-shelf treatment option for people with transplant-ineligible R/R DLBCL
  • Data were featured in the congress press briefing and presented in the Plenary Abstracts Session at EHA 2024 as a late-breaking oral presentation
More information: Media Release, 15 June 2024
Evrysdi
Spinal muscular atrophy 		Five-year data for Evrysdi show the majority of treated children with a severe form of spinal muscular atrophy achieved or maintained the ability to sit, stand or walk

  • After five years of treatment, 91% of children were alive — without treatment, children with type 1 SMA would not be expected to live past two years of age
  • 96% of children treated with Evrysdi could swallow, 80% could feed without a feeding tube and 59% could sit without support for at least 30 seconds
  • Evrysdi is now approved in more than 100 countries with over 15,000 patients treated globally
More information: Media Release, 7 June 2024
CT-388
Obesity

 

  		Positive phase Ib results for dual GLP-1/GIP receptor agonist CT-388 in people with obesity

  • Over 24 weeks, a once-weekly subcutaneous injection of CT-388 achieved a clinically meaningful and statistically significant mean placebo-adjusted weight loss of 18.8% (p < 0.001)
  • At week 24, 100% of CT-388 treated participants achieved >5% weight loss, 70% achieved >15% weight loss and 45% achieved >20% weight loss
  • In a subgroup with pre-diabetes at baseline, CT-388 treatment normalised glycaemia in all patients, indicating its strong impact on glucose homoeostasis
  • No new or unexpected safety signals were detected. Overall, CT-388 demonstrated a safety and tolerability profile consistent with its drug class
More information: Media Release, 16 May 2024

Pharmaceuticals sales

Sales CHF millions As % of sales % change
January–June 2024 2023 2024 2023 At CER In CHF
Pharmaceuticals Division 22,637 22,511 100.0 100.0 5 1
United States 11,882 11,573 52.5 51.4 5 3
Europe 4,425 4,105 19.5 18.2 10 8
Japan 1,366 2,210 6.0 9.8 -28 -38
International* 4,964 4,623 22.0 20.6 17 7

All figures shown in the table were restated to reflect the shift of the Foundation Medicine (FMI) business from the Pharmaceuticals Division to the Diagnostics Division.

*Asia-Pacific, CEETRIS (Central Eastern Europe, Türkiye, Russia and Indian subcontinent), Latin America, Middle East, Africa, Canada, other

Top-selling medicines Total United States Europe Japan International
CHF m % CHF m % CHF m % CHF m % CHF m %
Ocrevus
Multiple sclerosis 		3,359 8 2,411 5 639 12 - - 309 27
Hemlibra
Haemophilia A 		2,143 7 1,231 1 468 14 171 3 273 32
Perjeta3
Breast cancer 		1,921 -2 694 -7 341 -16 66 -30 820 14
Tecentriq
Cancer immunotherapy 		1,798 2 898 -8 429 10 182 -2 289 32
Vabysmo
Eye diseases (nAMD, DME, RVO) 		1,794 93 1,371 78 287 183 53 35 83 324
Actemra/RoActemra3
RA, COVID-19 		1,276 3 595 6 363 -3 146 7 172 4
Xolair3
Asthma 		1,110 10 1,110 10 - - - - - -
Kadcyla3
Breast cancer 		999 6 381 1 288 -1 46 2 284 23
Evrysdi
Spinal muscular atrophy 		838 25 283 14 286 21 44 14 225 50
Phesgo
Breast cancer 		799 60 258 27 354 51 50 - 137 115
Alecensa
Lung cancer 		766 7 236 9 145 1 96 4 289 10
Herceptin3
Breast and gastric cancer 		740 -11 138 -19 154 -14 8 -44 440 -5
MabThera/Rituxan3
Blood cancer, RA 		706 -17 422 -19 77 -17 9 -23 198 -11
Avastin 3
Various cancer types 		654 -16 199 -20 44 -20 102 -33 309 -4
Activase/TNKase3
Cardiac diseases 		593 -2 561 -3 - - - - 32 17
Polivy
Blood cancer 		513 54 255 112 86 9 92 -1 80 107
Gazyva/Gazyvaro3
Blood cancer 		445 15 217 14 123 13 15 -16 90 29
Pulmozyme3
Cystic fibrosis 		225 -2 141 -8 39 2 - 26 45 20
Madopar3
Parkinson’s disease 		200 13 - - 50 1 - - 150 17
CellCept3
Immunosuppressant 		197 4 12 -26 60 -5 18 -10 107 19

DME: diabetic macular oedema / nAMD: neovascular or ‘wet’ age-related macular degeneration / RVO: retinal vein occlusion / RA: rheumatoid arthritis

Diagnostics: key developments

Product Milestone
Accu-Chek SmartGuide
Diabetes management 		CE mark for AI-enabled continuous glucose monitoring solution offering critical predictions to people living with diabetes

  • The Accu-Chek SmartGuide CGM solution provides accurate real-time glucose values for adults living with type 1 and type 2 diabetes on flexible insulin therapy
  • The built-in AI-trained algorithms will empower users to proactively intervene when their glucose levels require attention and before a complication can even occur
  • The solution is set to launch in selected European markets in the coming months
More information: Media Release, 9 July 2024
cobas 5800, 6800 and 8800 systems
Human papillomavirus (HPV) 		Roche expands access to cervical cancer screening tools with two new WHO prequalification designations, including HPV self-collection

  • The World Health Organization (WHO) has awarded Roche’s human papillomavirus (HPV) test prequalification designations for use on the cobas 5800 system and for self-collected samples on the cobas 5800, 6800 and 8800 systems
  • These designations build upon last June’s WHO prequalification that included the cobas HPV test for use on the cobas 6800 and 8800 systems
  • WHO prequalification enables low- and middle-income countries (LMICs) to use Roche HPV screening solutions, including self-collection, in their national cervical cancer elimination programmes, which will greatly increase access
  • Every year, over 600,000 women worldwide are diagnosed with cervical cancer and over 340,000 die from this preventable disease caused by HPV infection. Nine out of 10 women who die from cervical cancer live in LMICs
More information: Media Release, 27 June 2024
cobas pro integrated solutions

 

  		Roche launches new analytical units for cobas pro integrated solutions delivering greater efficiency and capacity to laboratories

  • The cobas c 703 and cobas ISE neo analytical units deliver higher testing capacity and increased automation, helping to improve laboratory workflows and advance patient care
  • The new cobas c 703 analytical unit offers industry-leading high-throughput clinical chemistry testing with up to 2,000 tests per hour and 70 reagent positions, doubling the existing clinical chemistry throughput on cobas pro integrated solutions
  • The new cobas ISE neo analytical unit delivers more efficient ISE testing, reducing hands-on time through automated maintenance
More information: Media Release, 24 June 2024
VENTANA Kappa and Lambda Dual ISH mRNA Probe Cocktail assay
B-cell lymphoma 		Roche launches new highly sensitive test to more easily diagnose patients with B-cell lymphoma

  • The VENTANA Kappa and Lambda Dual ISH mRNA Probe Cocktail assay is the first clinically approved in-situ hybridisation (ISH) test with the sensitivity to assess the full spectrum of B-cell lymphoma subtypes
  • The test helps differentiate a B-cell cancer from a normal, reactive immune response, providing diagnostic certainty for healthcare providers and their patients
  • B-cell lymphoma accounts for approximately 85 percent of non-Hodgkin lymphoma (NHL) cases, which is the tenth most common cancer worldwide
More information: Media Release, 20 June 2024
cobas liat system
Infectious diseases

  		Roche four-in-one molecular test for SARS-CoV-2, Influenza A/B viruses and RSV receives US FDA Emergency Use Authorisation

  • The test uses highly sensitive PCR technology, requiring only a single nasal-swab sample to provide rapid, accurate qualitative detection and differentiation among four of the most prevalent respiratory viruses for which differential diagnosis can drive appropriate treatment
  • It enables healthcare professionals to make confident clinical decisions and promptly determine appropriate treatment, with definitive results reported in just 20 minutes
  • It expands Roche’s extensive molecular point-of-care testing portfolio, offering greater flexibility to meet testing needs amid evolving regional prevalence of respiratory infections
More information: Media Release, 10 June 2024
Tina-quant lipoprotein (a) RxDx
Cardiovascular diseases 		FDA Breakthrough Device Designation for blood test measuring Lp(a) – a key marker for hereditary cardiovascular risk

  • Approximately one in five people worldwide have elevated Lp(a) levels, putting them at increased risk of cardiovascular diseases including myocardial infarction and stroke
  • The Tina-quant Lp(a) assay measures lipoprotein (a) in a person’s bloodstream, and will be made available on Roche’s installed base of over 90,000 serum work area (SWA) systems worldwide
  • The test was developed in collaboration with Amgen
More information: Media Release, 22 May 2024
HPV self-collection solution
Human papillomavirus (HPV)

  		FDA approval for one of the first HPV self-collection solutions in the US, expanding access and screening options to help eliminate cervical cancer

  • More than half of all US cervical cancer patients are underscreened, which makes reducing barriers to sample collection and increasing access to screenings crucial to ultimately helping eliminate this deadly disease
  • Each year in the US, more than 13,000 patients are diagnosed with cervical cancer and approximately 4,000 die from this preventable disease, caused by HPV infection
  • Roche’s human papillomavirus (HPV) self-collection solution will improve access to testing by providing women the option to privately collect their own sample
More information: Media Release, 15 May 2024

Diagnostics sales

Sales CHF millions As % of sales % change
January–June 2024 2023 2024 2023 At CER In CHF
Diagnostics Division 7,211 7,268 100.0 100.0 5 -1
Customer Areas4            
Core Lab 4,069 3,935 56.4 54.1 10 3
Molecular Lab5 1,275 1,288 17.7 17.7 3 -1
Near Patient Care6 1,097 1,358 15.2 18.7 -14 -19
Pathology Lab 770 687 10.7 9.5 17 12
Regions            
Europe, Middle East and Africa 2,431 2,456 33.7 33.8 4 -1
North America5 2,163 2,110 30.0 29.0 5 3
Asia-Pacific 2,102 2,205 29.2 30.3 3 -5
Latin America 515 497 7.1 6.9 16 4

More information on Roche performance in the first half of 2024:

About Roche
Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world’s largest biotechnology company and the global leader in in vitro diagnostics. The company pursues scientific excellence to discover and develop medicines and diagnostics for improving and saving the lives of people around the world. We are a pioneer in personalised healthcare and want to further transform how healthcare is delivered to have an even greater impact. To provide the best care for each person we partner with many stakeholders and combine our strengths in Diagnostics and Pharma with data insights from the clinical practice.

In recognising our endeavour to pursue a long-term perspective in all we do, Roche has been named one of the most sustainable companies in the pharmaceuticals industry by the Dow Jones Sustainability Indices for the fifteenth consecutive year. This distinction also reflects our efforts to improve access to healthcare together with local partners in every country we work.

Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan.

For more information, please visit www.roche.com.

All trademarks used or mentioned in this release are protected by law.


References
[1] Unless otherwise stated, all growth rates and comparisons to the previous year in this document are at constant exchange rates (CER: average rates 2023) and all total figures quoted are reported in CHF.
[2] Pharmaceuticals Division base business: excluding COVID-19 medicine Ronapreve.
Diagnostics Division base business: excluding COVID-19-related products.
[3] Products launched before 2015.
[4] Core Lab: diagnostics solutions in the areas of immunoassays, clinical chemistry and CustomBiotech.
Molecular Lab: diagnostics solutions for pathogen detection and monitoring, donor screening, sexual health and genomics, genomic tumour profiling.
Near Patient Care: diagnostics solutions in emergency rooms, medical practices and directly with patients, including integrated personalised diabetes management.
Pathology Lab: diagnostics solutions for tissue biopsies and companion diagnostics.
[5] Sales in the Molecular Lab customer area include sales from the Foundation Medicine business which moved under the responsibility of the Diagnostics Division from the Pharmaceuticals Division effective 1 January 2024. The comparative information for 2023 has been restated accordingly.
[6] Sales in the new Near Patient Care customer area include sales from Diabetes Care and the Point of Care business, both previously shown as separate customer areas. The comparative information for 2023 has been restated accordingly.

Cautionary statement regarding forward-looking statements
This document contains certain forward-looking statements. These forward-looking statements may be identified by words such as ‘believes’, ‘expects’, ‘anticipates’, ‘projects’, ‘intends’, ‘should’, ‘seeks’, ‘estimates’, ‘future’ or similar expressions or by discussion of, among other things, strategy, goals, plans or intentions. Various factors may cause actual results to differ materially in the future from those reflected in forward-looking statements contained in this document, such as: (1) pricing and product initiatives of competitors; (2) legislative and regulatory developments and economic conditions; (3) delay or inability in obtaining regulatory approvals or bringing products to market; (4) fluctuations in currency exchange rates and general financial market conditions; (5) uncertainties in the discovery, development or marketing of new products or new uses of existing products, including without limitation negative results of clinical trials or research projects, unexpected side effects of pipeline or marketed products; (6) increased government pricing pressures; (7) interruptions in production; (8) loss of or inability to obtain adequate protection for intellectual property rights; (9) litigation; (10) loss of key executives or other employees; and (11) adverse publicity and news coverage. The statement regarding earnings per share growth is not a profit forecast and should not be interpreted to mean that Roche’s earnings or earnings per share for this or any subsequent period will necessarily match or exceed the historical published earnings or earnings per share of Roche.

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