Share and Bond information

The company has a share capital of CHF 106,691 divided into 106,691,000 fully paid-up bearer shares with a nominal value of CHF 0.001 each. There are no limitations on the transfer of these shares and no shares with maximum voting rights (please refer to § 3ss. of the Articles of Incorporation of Roche Holding Ltd.).

In addition, the company has a participation capital of CHF 702,562.70 divided into 702,562,700 fully paid-up bearer participation certificates with a nominal value of CHF 0.001 each.

For more information, please refer to the Articles of Incorporation.

At 31 December 2025, based on the information available to the Group, a shareholder group with pooled voting rights owned 69,318,000 shares representing 64.97% (2024: 64.97%) of the issued shares. On 5 December 2019 the shareholder group announced that it would continue the shareholder pooling agreement with a modified shareholder composition. This group now consists of Mr André Hoffmann, Ms Marie-Anne Hoffmann, Ms Vera Michalski, Mr Alexander Hoffmann, Mr Frederic Hoffmann, Ms Isabel Hoffmann, Mr Lucas Hoffmann, Ms Marina Hoffmann, Ms Kasia Larrieu-Barbotin, Ms Tatiana Fabre, Mr Andreas Oeri, Ms Catherine Oeri, Ms Sabine Duschmalé, Mr Jörg Duschmalé, Mr Lukas Duschmalé, the charitable foundation Wolf and Artuma Holding LLC. The shareholder pooling agreement has existed since 1948. The duration of the pool was extended for an indefinite period in 2009. At 31 December 2025, based on the information available to the Group, Ms Maja Oeri, formerly a member of the pool, held 4,045,950 shares independently of the pool, representing 3.79% (2024: 8,091,900 shares representing 7.58% of the issued shares). In addition, at 31 December 2025, based on the information available to the Company, Mr Melchior Oeri, held 4,045,950 shares independently of the pool, representing 3.79% of the issued shares (2024:none)

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• Bank of America

• Bank Vontobel AG

• Barclays

• Berenberg

• Bernstein

• Citi

• Cowen & Co

• Deutsche Bank

• Exane BNP Paribas

• HSBC

• Intron Health

• Jefferies

• JPMorgan

• Kepler Cheuvreux

• Morgan Stanley

• Morningstar Inc

• ODDO Securities

• Redburn (Europe) Limited

• Stifel

• UBS

• Wolfe Research

• Zürcher Kantonalbank (ZKB)